α-Crystallin assists the renaturation of glyceraldehyde-3-phosphate dehydrogenase
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چکیده
منابع مشابه
alpha-crystallin assists the renaturation of glyceraldehyde-3-phosphate dehydrogenase.
alpha-Crystallin, a major lens protein, has many of the properties of a molecular chaperone, but its ability to assist refolding of proteins has been less certain. In the present work it was shown that alpha-crystallin specifically increased the reactivation of guanidine-denatured glyceraldehyde-3-phosphate dehydrogenase with most of the activity being recovered. In the incubation mixture the r...
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comprises both an oxidation and a phosphorylation and must therefore consist of two successive steps. Until recently there was considerable doubt as to which came first, the oxidation or the phosphorylation. Early speculations (l-4) that the initial step was the uptake of phosphate to form a 1,3-diphosphoglyceraldehyde have proved impossible of confirmation (5-7), and it has recently become cle...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 2000
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj3450467